Incision care

Advanced care for high-risk incisions

Incisional Negative Pressure Wound Therapy (NPWT) with Avance® Solo

Since its commercial introduction, negative pressure wound therapy (NPWT) has transformed the management of open wounds1, It has also revolutionised incision care, proving that it offers clinical benefits, from reducing the incidence of surgical site infections2–7, dehiscence5–7 and oedema1,4 to improving blood flow8,9 and healing10. The clinically effective range of NPWT lies between –40 and –150 mmHg11. In a model comparing how well different NPWT systems can reduce peri-wound tension while operating at either –80 or –125 mmHg, –125 mmHg was found to be the most effective12. 

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Explore our resources on Avance® Solo and incisional NPWT

    1.  Karlakki S, Brem M, Giannini S, Khanduja V, Stannard J, Martin R. Negative pressure wound therapy for management of the surgical incision in orthopaedic surgery: a review of evidence and mechanisms for an emerging indication. Bone Joint Res. 2013;2(12):276–84. 
    2. Hyldig N, Birke-Sorensen H, Kruse M, Vinter C, Joergensen JS, Sorensen JA, et al. Meta-analysis of negative-pressure wound therapy for closed surgical incisions. British Journal of Surgery. 2016;103(5):477–486.
    3. Rashed A, Csiszar M, Beledi Á, Gombocz K. The impact of incisional negative pressure wound therapy on the wound healing process after midline sternotomy. Int Wound J. 2021;18(1):95–102. 
    4. Ailaney N, Johns WL, Golladay GJ, Strong B, Kalore NV. Closed incision negative pressure wound therapy for elective hip and knee arthroplasty: A systematic review and meta-analysis of randomized controlled trials. J Arthroplasty. 2021;36(7):2402–11.
    5. Pleger SP, Nink N, Elzien M, Kunold A, Koshty A, Böning A. Reduction of groin wound complications in vascular surgery patients using closed incision negative pressure therapy (ciNPT): A prospective, randomised, single-institution study. Int Wound J. 2018;15(1):75–83.
    6. Wikkelving M, van der Vlies CH, van der Laan L. The use of closed incision negative pressure therapy for incision and surrounding soft tissue management: Expert panel consensus recommendations. J Wound Care. 2021;30(9):705–10.e5.
    7. Naylor RM, Gilder HE, Gupta N, Hydrick TC, Labott JR, Mauler DJ, et al. Effects of negative pressure wound therapy on wound dehiscence and surgical site infection following instrumented spinal fusion surgery: A single surgeon's experience. World Neurosurg. 2020;137:e257–62.
    8. Atkins BZ, Wooten MK, Kistler J, Hurley K, Hughes GC, Wolfe WG. Does negative pressure wound therapy have a role in preventing poststernotomy wound complications? Int Wound J. 2011;8(1):56–62.
    9. Petzina R, Malmsjö M, Stamm C, Hetzer R. Major complications during negative pressure wound therapy in poststernotomy mediastinitis after cardiac surgery. Eur J Cardiothoracic Surg. 2010;37(6):1384–90.
    10. Pachowsky M, Gusinde J, Klein A, Lehrl S, Schulz-Drost S, Schlechtweg P. Negative pressure wound therapy to prevent seromas and treat surgical incisions after total hip arthroplasty. Int Orthop. 2012;36(4):719–22.
    11. Birk-Sorensen H, Malmsjo M, Rome P, Hudson D, Krug E, Berg L, et al. Evidence-based recommendations for negative pressure wound therapy: Treatment variables (pressure levels, wound filler and contact layer) – Steps towards an international consensus. J Plast Reconstr Aesthet Surg. 2011;64(Suppl 1):S1–16.
    12. Henriksson S. Poster #69 presented at: American Association of Hip and Knee Surgeons (AAHKS) Annual Meeting; 6–10 November 2024; Dallas, Texas, USA.
    13. Nherera LM, Trueman P, Schmoeckel M, Fatoye FA. Cost-effectiveness analysis of single use negative pressure wound therapy dressings compared to standard of care in reducing surgical site complications in patients undergoing coronary artery bypass grafting surgery. J Cardiothoracic Surg. 2018;13:103.
    14. Witt-Majchrzak A, Wójcik M, Majchrzak K, Majda K, Majchrzak J. Negative pressure wound therapy in the treatment of surgical wounds after vascular surgery. Pol Przegl Chir. 2015;86(10):456–65.
    15. Anderson V, Broad J, Streeter S, Wise L. The use of negative pressure wound therapy in midwifery practice. Evidence-Based Midwifery. 2014;12:23–8.
    16. Kuper TM, Murphy PB, Kwan D, Okrainec A, Quereshy FA, Cleary SP, Coburn NG. Negative pressure wound therapy for surgical incisions in high-risk patients undergoing vascular surgery. Ann Surg. 2020;271(1):67–74.
    17. Carter MR, Barnes SL, Williamson JS, Rowe VL, Weaver FA. Negative pressure wound therapy in vascular surgery: A pilot study. Irish J Med Sci. 2006;185(Suppl):S111.
    18. Licari L, Evans K, Hwang J, Konda SR, Egol KA. Negative pressure wound therapy in orthopedic trauma: A case series. Cureus. 2020;12(5):e8283.
    19. Svensson-Björk R, Zarrouk M, Asciutto G, Hasselmann J, Acosta S. Meta-analysis of negative pressure wound therapy of closed groin incisions in arterial surgery. Br J Surg. 2019;106(4):310–8.
    20. Conde-Green A, Chung TL, Holton LH 3rd, Hui-Chou HG, Zhu Y, Wang H. Negative pressure wound therapy in plastic surgery: A review. Ann Plast Surg. 2013;71(4):394–9.
    21. Kim PJ, Anghel EL. Negative-pressure wound therapy: A comprehensive review of the evidence. Plast Reconstr Surg. 2016;138(3 Suppl):129S–137S.
    22. Mölnlycke Health Care AB. Avance Solo NPWT System – Healthcare Professional Instructions for Use. 2020. Available from: https://www.molnlycke.co.uk/contentassets/bab0b9b641344d7b9698e313194fcac6/avance-solo-hcp-user-manual.pdf.
    23. Mölnlycke Health Care AB. Data on File (ref. 11).
    24. Mölnlycke Health Care AB. Data on File (ref. 18).
    25. Mölnlycke Health Care AB. Data on File (ref. 23).
    26. White R. Evidence for atraumatic soft silicone wound dressing use. Wounds UK. 2005;1(3):104–9.
    27. Zillmer R, Trøstrup H, Karlsmark T, Gottrup F. Biophysical effects of a wound dressing with soft silicone and a perforated silicone wound contact layer: A comparative study. J Wound Care. 2006;15(5):187–91.
    28. Waring MJ, Parsons D, Harding KG. An evaluation of the clinical performance of a silicone foam dressing. J Wound Care. 2011;20(9):412–22.
    29. White R. A multinational survey of the use of soft silicone dressings for wound management. Wounds UK. 2008;4:8–14.

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