Explore the Clean, Cover, Compress pathway — a coordinated approach using Granudacyn for wound cleansing, Mepilex Up for exudate management, and Mepi Press 2 for sustained compression therapy.
Healing a VLU isn't one decision. It's every decision.
Get the Decision GuideVenous ulcers, also called venous stasis ulcers, are among the most challenging chronic wounds to manage. This Vascular Disease Awareness Month, we're highlighting how every decision in venous ulcer care, from wound bed preparation through compression therapy, shapes the healing journey. Because every step counts.

With a VLU, the wound on the surface isn't the whole problem.
A venous leg ulcer requires addressing multiple factors. Debris in the wound bed can delay healing, drainage can harm nearby skin, and underlying venous insufficiency continues to contribute to the problem. Clean. Cover. Compress. Three essential steps that work together to support healing, because every step counts.
A connected approach to a complex wound
-
Healing a venous leg ulcer requires more than treating the wound itself. Debris in the wound bed can delay healing, drainage can harm nearby skin, and underlying venous insufficiency continues to contribute to the problem. Clean. Cover. Compress. Three essential steps that work together to support healing, because every step counts.
-

1. Clean
Prepare the wound.
Granudacyn® cleanses and moistens the wound bed, loosening wound bed debris without harming the fragile cells that drive healing.
-

2. Cover
Manage exudate.
Mepilex® Up absorbs and locks away exudate, protecting the wound and surrounding skin from the leakage and maceration that stall progress.
-

3. Compress
Apply compression.
Mepi™ Press 2 and Mepi™ Press 2 Lite deliver compression matched to the patient's ABI, treating the venous pressure at the root of the ulcer.
The products behind every step.
-
The section above is the approach. This is what powers it. Each product is built for one job in the venous ulcer management pathway, and built to work with the others.
-

-
Because you can't heal what you haven't cleaned.
Clean with Granudacyn®
A ready-to-use wound wash14 for cleansing and irrigating chronic, acute, and contaminated wounds.1 Non-cytotoxic and non-irritating to wounds and surrounding skin,2 it mechanically lifts microorganisms and debris,1 and may help reduce wound malodor through mechanical removal of debris.1 Once opened, Granudacyn maintains its microbial purity for up to 60 days.14
See How it Cleans
-
Because exudate that spreads is a problem that spreads.
Cover with Mepilex® Up
An advanced foam dressing for supporting effective wound exudate management.15 A patented dimpled foam structure pulls fluid in every direction, even against gravity, so exudate is drawn away from healthy skin instead of pooling against it.6,16 The result is fewer leaks, longer wear time, and fewer interruptions to healing.3,6-8
See Mepilex Up in Action
-

-

-
Because the right pressure depends on the patient.
Compress with Mepi™ Press 2 & Mepi™ Press 2 Lite
A two-layer compression therapy system12-13 with a built-in application indicator that takes the guesswork out of getting compression right.19 Mepi" Press 2 delivers ~40 mmHg for standard venous disease (ABI 0.81.3)12,17; Mepi" Press 2 Lite delivers ~30 mmHg for patients who need reduced compression (ABI 0.60.8)13,18. Both stay in place without extra fixation19, wear up to 7 days20, and tear by hand for easy application.19
Explore Both Systems
Make every step count.
Keep the Clean. Cover. Compress. pathway within reach with a practical decision guide designed to support confident venous ulcer care.
Get the decision guideMore than products. A partner at every step.
-
Better venous ulcer care takes more than what's in the box. Mölnlycke backs every product with the evidence, education, and support clinicians need to deliver connected care with confidence.

-
Innovative Products
Purpose-built for the real challenges of VLU care: wound preparation, exudate management, and compression.
-
Clinical Education
Practical training, tools, and resources that build clinician confidence, from onboarding a new protocol to everyday practice.
-
Patient Resources
Clear, easy-to-understand materials that help patients follow their care plan and stay engaged in their own healing.
-
Detailed Support
Knowledgeable reps and clinical resources that help teams put best practices into place and keep them there.
Give venous ulcers the connected care they need.
Ordering Information
-
Granudacyn®
Product Code Product/size Pcs/box Pcs/case HCPCS 360170 250 ml (8.5 fl oz) Spray cap 1 15 A6260
360171 500 ml (16.9 fl oz) Screw cap (Pour bottle) 1 12 A6260
360172 1000 ml (33.8 fl oz) Screw cap (Pour bottle) 1 6 A6260 360173 500 ml (16.9 fl oz) Spikeable cap (Instillation bottle) 1 12 A6260
360174 1000 ml (33.8 fl oz) Spikeable cap (Instillation bottle) 1 6 A6260
Mepilex® Up
Product Code Product/size Pcs/box Pcs/case HCPCS 212199 4" x 4" (10 x 10 cm) 10 40 A6209
212299 4" x 8" (10 x 20 cm) 10 30 A6210
212399 6" x 6" (15 x 15 cm) 10 30 A6210 212499 8" x 8" (20 x 20 cm) 10 30 A6211
Mepi™ Press 2
Product Code Product/size Sets/box HCPCS 300021 Layer 1: White Bandage - 10 cm x 6.5 m (stretched) 8 A6441
Layer 2: Brown Bandage - 10 cm x 8.2 m (stretched) 8 A6452
Mepi™ Press 2 Lite
Product Code Product/size Sets/box HCPCS 300031 Layer 1: White Bandage - 10 cm x 6.5 m (stretched) 8 A6441
Layer 2: Brown Bandage - 10 cm x 8.2 m (stretched) 8 A6454
-
References
- Intended use as cleared in the 510(k) K243415.
- 2. DI-7-372-0 Biocompatibility Report Wound Wash Solution FDA
- Mölnlycke Health Care. Data on file. 2024.
- Mölnlycke Health Care. Data on file. 2015.
- Franks PJ, Moody M, Moffatt CJ, Hiskett G, Gatto P, Davies C. Randomized trial of two foam dressings in the management of chronic venous ulceration. Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society. 2007;15(2):197-202.
- Mölnlycke Health Care. Data on file. 2024.
- Mölnlycke Health Care. Data on file. 2024.
- Mölnlycke Health Care. Data on file. 2024.
- Eytier C, Gazeau E, Beneteau G, Verfaillie G. Convenience and tolerance of the combination of a soft silicone foam dressing and a two-way stretch tubular bandage in the management of local wounds. An observational study conducted by 304 registered nurses (RNs) on 2,401 patients. Results of TeMpO study. Journal des plaies et cicatrisations. 2013;18(88):38-44.
- Mölnlycke Health Care. Data on file 2019.
- Mölnlycke Health Care. Data on file 2021.
- Mölnlycke Health Care. Data on file 2025.
- Mölnlycke Health Care. Data on file 2025.
- Shelf Life WWS_FDA (DI-7-369-0); 510(k) submission K243415
- Mölnlycke Health Care. Instructions for Use, Mepilex® Up.
- Mölnlycke Health Care. Patent EP3198.
- Mölnlycke Health Care. Data on file 2025.
- Mölnlycke Health Care. Data on file 2025.
- Mepi Press 2 & 2 Lite Useability Report (KOB)
- Mepi Press 2 & 2 Lite Clinical Evaluation Report (KOB)